Impact of Preoperative Marijuana Use on Functional Recovery and Complications After Spinopelvic Fusion in Adult Spinal Deformity
BACKGROUND AND OBJECTIVES: With the rising prevalence of marijuana use and increasing rates of complex spinal deformity surgeries, understanding the impact of cannabis on perioperative outcomes is crucial. Previous studies yield mixed results on fusion success, complications, and opioid use in spine surgery, but none have focused on long-segment spinopelvic fusions. METHODS: < .05 considered significant. RESULTS: = .434). CONCLUSION: In this cohort, preoperative marijuana use was not associated with statistically significant differences in complication rates or inferior outcomes after long-segment spinopelvic fusion. Users experienced enhanced functional recovery, although this finding must be interpreted in the context of their higher baseline disability. Given the modest sample size, these findings should be viewed as preliminary; prospective studies with standardized cannabis exposure metrics are needed to confirm these results.
Authors
- Mohsen Rostami
- Puya Alikhani (ORCID: https://orcid.org/0009-0005-4075-6173)
- Srujan Kopparapu (ORCID: https://orcid.org/0000-0002-5862-7063)
- Sadegh Bagherzadeh (ORCID: https://orcid.org/0009-0000-1545-9218)
- Diego Soto Rubio
- Casey Ryan
- Jay Kumar
- Patrick Kim
- Dana Saleh
Institutions
- University of South Florida (US)
- Shariati Hospital (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Neurosurgery Open
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1227/neuprac.0000000000000218
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00