Impact of Preoperative Marijuana Use on Functional Recovery and Complications After Spinopelvic Fusion in Adult Spinal Deformity

BACKGROUND AND OBJECTIVES: With the rising prevalence of marijuana use and increasing rates of complex spinal deformity surgeries, understanding the impact of cannabis on perioperative outcomes is crucial. Previous studies yield mixed results on fusion success, complications, and opioid use in spine surgery, but none have focused on long-segment spinopelvic fusions. METHODS: < .05 considered significant. RESULTS: = .434). CONCLUSION: In this cohort, preoperative marijuana use was not associated with statistically significant differences in complication rates or inferior outcomes after long-segment spinopelvic fusion. Users experienced enhanced functional recovery, although this finding must be interpreted in the context of their higher baseline disability. Given the modest sample size, these findings should be viewed as preliminary; prospective studies with standardized cannabis exposure metrics are needed to confirm these results.

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Publication Details

Journal
Neurosurgery Open
Published
2026-04-01
DOI
https://doi.org/10.1227/neuprac.0000000000000218
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
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article

Impact of Preoperative Marijuana Use on Functional Recovery and Complications After Spinopelvic Fusion in Adult Spinal Deformity

Mohsen Rostami, Puya Alikhani, Srujan Kopparapu, Sadegh Bagherzadeh et al.
Neurosurgery Open
Spine and Intervertebral Disc Pathology
article

Impact of Preoperative Marijuana Use on Functional Recovery and Complications After Spinopelvic Fusion in Adult Spinal Deformity

Mohsen Rostami, Puya Alikhani, Srujan Kopparapu, Sadegh Bagherzadeh, Diego Soto Rubio, Casey Ryan, Jay Kumar, Patrick Kim, Dana Saleh
article en

Abstract

BACKGROUND AND OBJECTIVES: With the rising prevalence of marijuana use and increasing rates of complex spinal deformity surgeries, understanding the impact of cannabis on perioperative outcomes is crucial. Previous studies yield mixed results on fusion success, complications, and opioid use in spine surgery, but none have focused on long-segment spinopelvic fusions. METHODS: < .05 considered significant. RESULTS: = .434). CONCLUSION: In this cohort, preoperative marijuana use was not associated with statistically significant differences in complication rates or inferior outcomes after long-segment spinopelvic fusion. Users experienced enhanced functional recovery, although this finding must be interpreted in the context of their higher baseline disability. Given the modest sample size, these findings should be viewed as preliminary; prospective studies with standardized cannabis exposure metrics are needed to confirm these results.

Neurosurgery OpenVol. 7(2)
University of South Florida (US), Shariati Hospital (IR), Tehran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 29%
Spine and Intervertebral Disc Pathology
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