Platelet-related hematologic markers and genetic associations of aspirin resistance in kawasaki disease
as a candidate variant linked to KD-AR. These findings suggest that AR in KD represents a multifactorial phenotype involving immune-driven platelet dysregulation and genetic susceptibility. Baseline inflammatory indices, particularly NLR and SII, may assist in early identification of KD patients at increased likelihood of AR.
Authors
- Wan Seok Yang (ORCID: https://orcid.org/0000-0003-0017-3991)
- Jianrui Wei (ORCID: https://orcid.org/0000-0002-4556-1114)
- Xiangna Yang
- Chunjiao Wei
- Linjie Jiang
- Kaining Chen (ORCID: https://orcid.org/0000-0003-4878-0918)
- Huazhong Zhou (ORCID: https://orcid.org/0000-0002-7713-503X)
- Lei Pi (ORCID: https://orcid.org/0000-0002-0924-1316)
- Lanyan Fu
- Zheng Wang (ORCID: https://orcid.org/0000-0003-4873-505X)
- Yufen Xu (ORCID: https://orcid.org/0000-0002-0858-5715)
- Xia Gu (ORCID: https://orcid.org/0000-0003-1854-9125)
- Xilian Luo
- Caiting Xiao
- Xiaoting Ding
- Xiaoxue Li
Institutions
- Guangzhou Women and Children Medical Center (CN)
- Huashan Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2026-04-01
- DOI
- https://doi.org/10.3389/fmolb.2026.1807254
- Primary Topic
- Kawasaki Disease and Coronary Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guangzhou Medical University
- National Natural Science Foundation of China
- Guangzhou Institute of Pediatrics, Guangzhou Women and Childrens Medical Center