Two-Dimensional Sagittal-Plane Gait Evaluation and Similarity Analysis in Parkinson’s Disease Under ON and OFF Conditions: A Pilot Study

These findings demonstrate that sagittal-plane knee kinematics and interlimb coordination metrics derived from low-cost 2D videogrammetry are sensitive to the dopaminergic state and reveal persistent neuromotor deficits in PD. The proposed framework provides an interpretable and accessible approach for characterizing gait organization in Parkinson's disease and supports future integration with clinical assessment and longitudinal monitoring.