The Effect of Wildfire Exposure: Neurological Outcomes, Mental Health, and Epigenetic Insights

Current evidence suggests that wildfire exposure may influence neurological and mental health outcomes through biological and psychosocial pathways. However, the literature remains heterogeneous, and the independent effects of wildfire smoke exposure are often difficult to disentangle from disaster-related stressors. In addition, human evidence linking wildfire exposure to epigenetic changes remains limited, restricting causal inference. Further longitudinal and mechanistic studies integrating exposure assessment, neurological outcomes, and molecular profiling are needed to clarify these relationships.

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Publication Details

Journal
Genes
Published
2026-04-01
DOI
https://doi.org/10.3390/genes17040420
Primary Topic
Fire effects on ecosystems
Type
article
Field-Weighted Citation Impact
0.00
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article

The Effect of Wildfire Exposure: Neurological Outcomes, Mental Health, and Epigenetic Insights

Lei Cao-Lei, Haneen Abou El Khair, Venika Toor
Genes
Fire effects on ecosystems
article

The Effect of Wildfire Exposure: Neurological Outcomes, Mental Health, and Epigenetic Insights

Lei Cao-Lei, Haneen Abou El Khair, Venika Toor
article en

Abstract

Current evidence suggests that wildfire exposure may influence neurological and mental health outcomes through biological and psychosocial pathways. However, the literature remains heterogeneous, and the independent effects of wildfire smoke exposure are often difficult to disentangle from disaster-related stressors. In addition, human evidence linking wildfire exposure to epigenetic changes remains limited, restricting causal inference. Further longitudinal and mechanistic studies integrating exposure assessment, neurological outcomes, and molecular profiling are needed to clarify these relationships.

GenesVol. 17(4)
University of Ottawa (CA)
Climate action
Openalex Percentile: Top 28%
Fire effects on ecosystems
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