Quality of life in Turkish children with interstitial lung disease: Insights from the National chILD Registry
have an earlier diagnosis of age of chILD, lower FEV1%, higher Fan scores, and lower Child Self-Reports and Parent Reports scores (p < 0.05). The group with DPLD-A disorders has an earlier diagnosis age, lower weight and BMI z-scores, higher Fan score, and higher Family Impact Module score (p < 0.05). CONCLUSION: Lung function and Fan score strongly correlate with HRQoL, emphasizing the impact of disease severity on physical and psychosocial well-being. These findings highlight the need for multidisciplinary care and psychosocial support to enhance the QoL in children with chILD and their families. WHAT IS KNOWN: •Childhood interstitial lung diseases (chILD) are rare and diverse disorders associated with significant morbidity and complex management. •Evidence regarding health-related quality of life (HRQoL) and the psychosocial burden on affected families remains limited. WHAT IS NEW: •This multicenter national registry-based study provides the first comprehensive evaluation of HRQoL and family impact in children with chILD in Türkiye. •Lung function impairment and higher Fan severity scores were strongly linked to poorerHRQoL, highlighting the influence of disease severity on physical and psychosocial well-being.
Authors
- Ela Erdem Eralp
- Bahar Girgin Dindar (ORCID: https://orcid.org/0000-0002-0523-4856)
- Mahir Serbes (ORCID: https://orcid.org/0000-0001-6422-2639)
- Saniye Girit
- Güzin Cinel (ORCID: https://orcid.org/0000-0002-6209-196X)
- Fatma Nur Ayman (ORCID: https://orcid.org/0000-0002-8252-7775)
- Ahmet Cevdet Ceylan (ORCID: https://orcid.org/0000-0003-4938-3420)
- Berrak Öztosun (ORCID: https://orcid.org/0000-0001-5649-8045)
- Pelin Asfuroğlu (ORCID: https://orcid.org/0000-0002-9575-3982)
- Ayşe Ayzıt Kılınç Sakallı
- Ayşen Bingöl (ORCID: https://orcid.org/0000-0002-0886-3332)
- S Pekcan
- N Emiralioğlu
- Zeynep Seda Uyan (ORCID: https://orcid.org/0000-0002-7540-3467)
- B Oguz
- Beste Özsezen (ORCID: https://orcid.org/0000-0002-0052-8361)
- Umay Kavgacı
- Handan Kekeç (ORCID: https://orcid.org/0000-0001-8770-0939)
- Mina Hızal (ORCID: https://orcid.org/0000-0002-6922-4948)
- Aslıhan Ozcaglar
- Tuğba Ramaslı Gürsoy
- Nazan Çobanoğlu
- Özge Ülgen
- Ayse Tana Aslan
- Halime Nayır Buyuksahın
- S. Karabulut
- Diclehan Orhan
- Meltem Akgul Erdal
- Nural Kiper
- Yasemin Gökdemir
- Betül Bankoglu Parlak
- Esin Gizem Olgun
- Gözde Cavıldak Karaaslan
- Ebru Yalcın
- Cigdem Korkmaz
- Tugba Sismanlar Eyuboglu
Institutions
- Ministry of Health (TR)
- Koç University (TR)
- Ankara University (TR)
- Bilkent University (TR)
- Dokuz Eylül University (TR)
- Akdeniz University (TR)
- Mardin Artuklu University (TR)
- Istanbul Medipol University (TR)
- Ege University (TR)
- Dr. Behçet Uz Çocuk Hastalıkları Hastanesi (TR)
- Gaziantep Children's Hospital (TR)
- Necmettin Erbakan University (TR)
- Istanbul University-Cerrahpaşa (TR)
- Education Training And Research (US)
- Başkent University Hospital (TR)
- Cukurova University (TR)
- Istanbul Medeniyet University (TR)
- Hacettepe University (TR)
- Marmara University (TR)
- Gazi University (TR)
Publication Details
- Journal
- European Journal of Pediatrics
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1007/s00431-026-06834-5
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gazi Üniversitesi