Divergent Synthesis of Meyers’ Lactams and Medium Lactams via Cyclocondensation of γ-Ylidene-Butanolides with Chiral Amino Alcohols

-enol ether segment. This divergent synthetic strategy enables the efficient generation of a library of Meyers' lactams and medium lactams with good yields and diastereoselectivity.

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Publication Details

Journal
The Journal of Organic Chemistry
Published
2026-04-01
DOI
https://doi.org/10.1021/acs.joc.6c00086
Primary Topic
Asymmetric Synthesis and Catalysis
Type
article
Field-Weighted Citation Impact
0.00

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article

Divergent Synthesis of Meyers’ Lactams and Medium Lactams via Cyclocondensation of γ-Ylidene-Butanolides with Chiral Amino Alcohols

Ravindar Kontham, Rajesh G. Gonnade, Megha V Sadanande, Paridhi Sharma
The Journal of Organic Chemistry
Asymmetric Synthesis and Catalysis
article

Divergent Synthesis of Meyers’ Lactams and Medium Lactams via Cyclocondensation of γ-Ylidene-Butanolides with Chiral Amino Alcohols

Ravindar Kontham, Rajesh G. Gonnade, Megha V Sadanande, Paridhi Sharma
article en

Abstract

-enol ether segment. This divergent synthetic strategy enables the efficient generation of a library of Meyers' lactams and medium lactams with good yields and diastereoselectivity.

The Journal of Organic ChemistryVol. 91(14)
National Chemical Laboratory (IN), Academy of Scientific and Innovative Research (IN)
Council of Scientific and Industrial Research, India
Openalex Percentile: Top 30%
Asymmetric Synthesis and Catalysis
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