Transient tumor exposure induces persistent functional defects in memory CD8+ T cells
T cells. These findings highlight how suboptimal priming conditions during tumor challenge durably shape memory T cell responses.
Authors
- Sophia Djebali (ORCID: https://orcid.org/0000-0002-0567-5387)
- M. Dubois (ORCID: https://orcid.org/0009-0003-1575-1237)
- Margaux Prieux (ORCID: https://orcid.org/0000-0002-9750-9828)
- Daphné Laubreton (ORCID: https://orcid.org/0000-0001-9506-6755)
- Jacqueline Marvel (ORCID: https://orcid.org/0000-0001-6241-459X)
- Christophe Arpin (ORCID: https://orcid.org/0000-0003-0915-5554)
- Olivier Gandrillon (ORCID: https://orcid.org/0000-0002-3676-6513)
- Simon de Bernard (ORCID: https://orcid.org/0000-0002-3390-0924)
Institutions
- Université Claude Bernard Lyon 1 (FR)
- École Normale Supérieure de Lyon (FR)
- Centre National de la Recherche Scientifique (FR)
- Institut national de recherche en sciences et technologies du numérique (FR)
- Inserm (FR)
Publication Details
- Journal
- iScience
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1016/j.isci.2026.115556
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- Centre National de la Recherche Scientifique
- Conseil Régional d'Auvergne
- Université de Lyon