Next-generation digital twin model with unobtrusive RF multi-sensing for AI-based human monitoring

In healthcare, Digital Twin (DT) model can create real-time digital representations of patients' physiological states, enabling intelligent, data-driven decision-making for continuous monitoring and personalized treatment-without the invasiveness of traditional methods. This study presents a next-generation RF-powered DT model, integrating AI-driven analytics with multi-vital human sensing to establish a virtualized, self-learning, and adaptive framework for health monitoring. Leveraging unobtrusive Radio Frequency (RF) sensors, advanced signal processing, and Artificial Intelligence (AI), the proposed DT model facilitates continuous, non-contact assessment of respiration and exhaled hydration, ensuring a scalable, cost-effective, and efficient approach to real-time physiological monitoring. This work integrates unobtrusive ESP32 Wi-Fi sensors with Channel State Information (CSI) for respiration tracking and flexible UWB RF sensors for hydration monitoring. Enhanced signal processing achieves 100% accurate estimation of Breaths Per Minute (BPM) within the accepted inter-observer variability threshold (±5 BPM) from raw respiration data. To overcome the challenge of limited real-world respiration and hydration datasets, novel statistical augmentation methods are employed to generate synthetic data, validated through cross-correlation techniques (Pearson, Kendall, and Spearman). AI models, including supervised and semi-supervised Machine Learning (ML) and Deep Learning (DL), are implemented for binary and multi-class classification of respiration and hydration data. Random Forest achieves top accuracies of 88% (binary) and 69% (multi-class) in semi-supervised classification, while Decision Tree attains 89% and 83% accuracy in supervised exhaled hydration classification. Additionally, K-Nearest Neighbors (KNN) achieves 93% (binary) and 89% (multi-class) accuracy in semi-supervised hydration classification.

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Publication Details

Journal
Scientific Reports
Published
2026-04-01
DOI
https://doi.org/10.1038/s41598-026-43984-w
Primary Topic
Non-Invasive Vital Sign Monitoring
Type
article
Field-Weighted Citation Impact
0.00

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article

Next-generation digital twin model with unobtrusive RF multi-sensing for AI-based human monitoring

Usman Anwar, Sagheer Khan, Aaesha Alzaabi, Imran Saied et al.
Scientific Reports
Non-Invasive Vital Sign Monitoring
article

Next-generation digital twin model with unobtrusive RF multi-sensing for AI-based human monitoring

Usman Anwar, Sagheer Khan, Aaesha Alzaabi, Imran Saied, Tughrul Arslan, Kiran Khurshid
article en

Abstract

In healthcare, Digital Twin (DT) model can create real-time digital representations of patients' physiological states, enabling intelligent, data-driven decision-making for continuous monitoring and personalized treatment-without the invasiveness of traditional methods. This study presents a next-generation RF-powered DT model, integrating AI-driven analytics with multi-vital human sensing to establish a virtualized, self-learning, and adaptive framework for health monitoring. Leveraging unobtrusive Radio Frequency (RF) sensors, advanced signal processing, and Artificial Intelligence (AI), the proposed DT model facilitates continuous, non-contact assessment of respiration and exhaled hydration, ensuring a scalable, cost-effective, and efficient approach to real-time physiological monitoring. This work integrates unobtrusive ESP32 Wi-Fi sensors with Channel State Information (CSI) for respiration tracking and flexible UWB RF sensors for hydration monitoring. Enhanced signal processing achieves 100% accurate estimation of Breaths Per Minute (BPM) within the accepted inter-observer variability threshold (±5 BPM) from raw respiration data. To overcome the challenge of limited real-world respiration and hydration datasets, novel statistical augmentation methods are employed to generate synthetic data, validated through cross-correlation techniques (Pearson, Kendall, and Spearman). AI models, including supervised and semi-supervised Machine Learning (ML) and Deep Learning (DL), are implemented for binary and multi-class classification of respiration and hydration data. Random Forest achieves top accuracies of 88% (binary) and 69% (multi-class) in semi-supervised classification, while Decision Tree attains 89% and 83% accuracy in supervised exhaled hydration classification. Additionally, K-Nearest Neighbors (KNN) achieves 93% (binary) and 89% (multi-class) accuracy in semi-supervised hydration classification.

Scientific Reports
German Research Centre for Artificial Intelligence (DE), National Microelectronics Institute (GB), National University of Sciences and Technology (PK), University of Edinburgh (GB)
University of Edinburgh
Openalex Percentile: Top 16%
Non-Invasive Vital Sign Monitoring
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