Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Authors

Edward Avezov (ORCID: https://orcid.org/0000-0002-2894-0585)
Joseph E. Chambers (ORCID: https://orcid.org/0000-0003-4675-0053)
Elena F. Koslover (ORCID: https://orcid.org/0000-0003-4139-9209)
Tasuku Konno (ORCID: https://orcid.org/0000-0002-4983-5805)
Daniel C. Maddison (ORCID: https://orcid.org/0000-0003-3038-1687)
Valentina Davì
Mosab Ali Awadelkareem (ORCID: https://orcid.org/0000-0001-6898-6310)
Michael J. Devine (ORCID: https://orcid.org/0000-0001-6076-3382)
Pierre Parutto (ORCID: https://orcid.org/0000-0002-9866-407X)
Cécile C. Crapart (ORCID: https://orcid.org/0000-0002-7065-7791)
E.T. Gomes
Yuyi Zhang
Raquel Pereira
John P. Franklin

Institutions

University of Lisbon (PT)
Queen Mary University of London (GB)
King's College London (GB)
Wellcome/MRC Cambridge Stem Cell Institute (GB)
The Francis Crick Institute (GB)
University of California San Diego (US)
University of Oxford (GB)
Hospital de Egas Moniz (PT)
UK Dementia Research Institute (GB)
University College London (GB)
Instituto Gulbenkian de Ciência (PT)
Universidade Nova de Lisboa (PT)

Publication Details

Journal: Advanced Science
Published: 2026-03-31
DOI: https://doi.org/10.1002/advs.202521101
Citations: 1
Primary Topic: Cellular transport and secretion
Type: article
Field-Weighted Citation Impact: 12.79

Funders

National Science Foundation
Wellcome Trust
Francis Crick Institute
Alzheimer's Society
Alzheimer Society
Cancer Research UK
European Commission
Cambridge Trust
Evelyn Trust
UK Dementia Research Institute
Medical Research Council

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article

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Edward Avezov, Joseph E. Chambers, Elena F. Koslover, Tasuku Konno et al.

Mar 31, 2026

1 citations

Advanced Science

Cellular transport and secretion

12.79

article

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Edward Avezov, Joseph E. Chambers, Elena F. Koslover, Tasuku Konno, Daniel C. Maddison, Valentina Davì, Mosab Ali Awadelkareem, Michael J. Devine, Pierre Parutto, Cécile C. Crapart, E.T. Gomes, Yuyi Zhang, Raquel Pereira, John P. Franklin

March 31, 2026article en

1 citations

Abstract

No abstract available for this paper.

Advanced Science

University of Lisbon (PT), Queen Mary University of London (GB), King's College London (GB), Wellcome/MRC Cambridge Stem Cell Institute (GB), The Francis Crick Institute (GB), University of California San Diego (US), University of Oxford (GB), Hospital de Egas Moniz (PT), UK Dementia Research Institute (GB), University College London (GB), Instituto Gulbenkian de Ciência (PT), Universidade Nova de Lisboa (PT)

National Science Foundation, Wellcome Trust, Francis Crick Institute, Alzheimer's Society, Alzheimer Society, Cancer Research UK, European Commission, Cambridge Trust, Evelyn Trust, UK Dementia Research Institute, Medical Research Council

Openalex Percentile: Top 1%

Cellular transport and secretion

12.79

DOI Open Access PDF OpenAlex

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