Linalool, linalyl acetate, and lavender essential oil: evaluation of metabolism and drug interactions using canine liver microsomes and recombinant enzymes
metabolites generated by other CYPs in pDLMs.These findings highlight CYP2B11 and CYP2C21 as key enzymes in LIN and LINAc metabolism and underscore the potential for herb-drug interactions when treating dogs with lavender essential oil.
Authors
- Renata Cristina Mendes Ferreira (ORCID: https://orcid.org/0000-0001-6226-0623)
- Michael H. Court (ORCID: https://orcid.org/0000-0002-2122-9977)
- Raquel Rodrigues Soares Santos (ORCID: https://orcid.org/0000-0002-2089-8781)
- Benito Soto-Blanco
Institutions
- Universidade Federal de Minas Gerais (BR)
- Foundation for Individual Rights in Education (US)
Publication Details
- Journal
- Xenobiotica
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1080/00498254.2026.2654087
- Primary Topic
- Pharmacogenetics and Drug Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico