Optimized Mixture of Essential Oils From <i>Thymus capitatus</i> , <i>Rosmarinus officinalis</i> , and <i>Aloysia citrodora</i> : Synergistic Antidiabetic and Antioxidant Activities With Reduced Cytotoxicity
= 5.11 µg/mL). The results demonstrate the efficacy of mixture design in balancing potency and safety, proposing the optimized essential oil blend as a promising low-toxicity candidate for the adjuvant management of diabetes and oxidative stress, warranting further in vivo validation.
Authors
- Sarra Bachkouel (ORCID: https://orcid.org/0000-0002-7692-8660)
- Soumaya Bourgou (ORCID: https://orcid.org/0000-0002-9690-5685)
- Nicolò Maria Ippolito (ORCID: https://orcid.org/0009-0002-3451-1469)
- Sarra Dakhlaoui (ORCID: https://orcid.org/0000-0002-1538-0582)
- Lina Ammar
- Kamel Msaâda (ORCID: https://orcid.org/0000-0003-4826-8041)
- Mariem BenJemaa
- Ghada Hassine
Institutions
- University of L'Aquila (IT)
- Research and Technology Center of Energy (TN)
- Center of Biotechnogy of Borj Cédria (TN)
Publication Details
- Journal
- Chemistry & Biodiversity
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1002/cbdv.202503735
- Primary Topic
- Essential Oils and Antimicrobial Activity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Higher Education and Scientific Research