Post–Myocardial Infarction Ventricular Septal Defect Percutaneous Closure

BACKGROUND: Ventricular septal rupture is an uncommon but serious complication of late post-myocardial infarctions (MI) with an exceedingly high mortality. The American College of Cardiology and American Heart Association still advise immediate surgical closure of ventricular septal rupture. CASE SUMMARY: We described a novel minimally invasive transcatheter approach to post-MI ventricular septal defect (PMIVSD) closure through a venovenous loop for an 82-year-old woman. DISCUSSION: A PMIVSD is typically treated surgically and offers reasonable outcomes in patients who survive an initial healing phase. Transcatheter approaches serve as a potential treatment option for select high-risk surgical candidates. TAKE-HOME MESSAGES: Transcatheter closure is a viable alternative in high-risk PMIVSD patients unsuitable for surgery. A venovenous loop offers a safe and effective route for percutaneous VSD closure.