Retrospective Cohort Analysis of TyG, TyG-SI, and TyG-Lac Indices as Predictors of 360-Day Mortality in Critically Ill Ischemic Stroke Patients

: When analyzed as continuous variables, each of the three indices demonstrated significant associations with 360-day mortality risk of critically ill IS populations. Moreover, both TyG-SI and TyG can improve the 360-day mortality predictive accuracy of the base model. Among the three indices, TyG-SI showed comparatively better discriminatory performance; however, the magnitude of AUC improvement was modest, and its clinical utility should be interpreted cautiously pending external validation.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-01
DOI
https://doi.org/10.3390/jcm15072680
Primary Topic
Hyperglycemia and glycemic control in critically ill and hospitalized patients
Type
article
Field-Weighted Citation Impact
0.00

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article

Retrospective Cohort Analysis of TyG, TyG-SI, and TyG-Lac Indices as Predictors of 360-Day Mortality in Critically Ill Ischemic Stroke Patients

J. Liu, Wei Wang, Hao Fan, Chao Zhang et al.
Journal of Clinical Medicine
Hyperglycemia and glycemic control in critically ill and hospitalized patients
article

Retrospective Cohort Analysis of TyG, TyG-SI, and TyG-Lac Indices as Predictors of 360-Day Mortality in Critically Ill Ischemic Stroke Patients

J. Liu, Wei Wang, Hao Fan, Chao Zhang, Huaibin Liang
article en

Abstract

: When analyzed as continuous variables, each of the three indices demonstrated significant associations with 360-day mortality risk of critically ill IS populations. Moreover, both TyG-SI and TyG can improve the 360-day mortality predictive accuracy of the base model. Among the three indices, TyG-SI showed comparatively better discriminatory performance; however, the magnitude of AUC improvement was modest, and its clinical utility should be interpreted cautiously pending external validation.

Journal of Clinical MedicineVol. 15(7)
Shanghai Ninth People's Hospital (CN)
National Natural Science Foundation of China
Reduced inequalities
Openalex Percentile: Top 30%
Hyperglycemia and glycemic control in critically ill and hospitalized patients
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