Modeling an SPR Sensor for Carcinoma-Related Refractive-Index Detection: The Case of CaF2/Au/Si3N4/BP Multilayer System
in the same regime. Composite indicators (figure of merit and contrast signal factor) peak at intermediate levels, whereas resonance broadening at higher levels reduces the quality factor and increases the inferred limit of detection, evidencing a sensitivity-resolution trade-off. Benchmarking against reported SPR platforms indicates that BP-assisted interface engineering provides a competitive low-level operating window within a preliminary refractive-index-sensing framework that is relevant to future biosensor design. These results motivate further experimental validation, including BP stabilization, surface biofunctionalization, and practical implementation under liquid-phase sensing conditions.
Authors
- Cristian Vacacela Gómez (ORCID: https://orcid.org/0000-0002-9248-9944)
- Talía Tene (ORCID: https://orcid.org/0000-0002-8588-6490)
- Martha Ximena Dávalos Villegas
Institutions
- Universidad Técnica Particular de Loja (EC)
- Escuela Superior Politécnica del Chimborazo (EC)
- Universidad Ecotec (EC)
- University of Calabria (IT)
Publication Details
- Journal
- Biosensors
- Published
- 2026-04-01
- DOI
- https://doi.org/10.3390/bios16040198
- Primary Topic
- Plasmonic and Surface Plasmon Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidad Técnica Particular de Loja