Evaluation and management of premenstrual dysphoric disorder

PURPOSE OF REVIEW: Premenstrual dysphoric disorder (PMDD) is a condition that impacts the quality of life of those affected. Diagnosis can be difficult and lead to delays in treatment. In this article, we review current evidence for the evaluation and treatment of PMDD relevant to pediatric providers and their patients. RECENT FINDINGS: Recent research emphasizes the difficulties that patients with PMDD face in presenting to care and receiving appropriate diagnosis and treatment. Some of these challenges appear to be exacerbated among populations with comorbid mental health disorders and/or marginalized identities. While there are longstanding data supporting the use of selective serotonin-reuptake inhibitors and oral contraceptive pills in managing PMDD, emerging research provides insight on disease pathophysiology, mechanisms of action for current treatments, and potential horizons for new management options. SUMMARY: This article aims to provide practical guidelines for pediatricians to use in the initial evaluation and management of PMDD with special considerations for diverse populations.

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Publication Details

Journal
Current Opinion in Pediatrics
Published
2026-03-31
DOI
https://doi.org/10.1097/mop.0000000000001563
Primary Topic
Menstrual Health and Disorders
Type
article
Field-Weighted Citation Impact
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article

Evaluation and management of premenstrual dysphoric disorder

Pamela J. Murray, Emily Allen, Shea A. Nagle
Current Opinion in Pediatrics
Menstrual Health and Disorders
article

Evaluation and management of premenstrual dysphoric disorder

Pamela J. Murray, Emily Allen, Shea A. Nagle
article en

Abstract

PURPOSE OF REVIEW: Premenstrual dysphoric disorder (PMDD) is a condition that impacts the quality of life of those affected. Diagnosis can be difficult and lead to delays in treatment. In this article, we review current evidence for the evaluation and treatment of PMDD relevant to pediatric providers and their patients. RECENT FINDINGS: Recent research emphasizes the difficulties that patients with PMDD face in presenting to care and receiving appropriate diagnosis and treatment. Some of these challenges appear to be exacerbated among populations with comorbid mental health disorders and/or marginalized identities. While there are longstanding data supporting the use of selective serotonin-reuptake inhibitors and oral contraceptive pills in managing PMDD, emerging research provides insight on disease pathophysiology, mechanisms of action for current treatments, and potential horizons for new management options. SUMMARY: This article aims to provide practical guidelines for pediatricians to use in the initial evaluation and management of PMDD with special considerations for diverse populations.

Current Opinion in Pediatrics
Boston Children's Hospital (US), Harvard University (US), Brown University (US), Hasbro Children's Hospital (US)
Openalex Percentile: Top 27%
Menstrual Health and Disorders
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Evaluation and management of premenstrual dysphoric disorder — Pamela J. Murray, Emily Allen, et al. · Current Opinion in Pediatrics (2026) | TGRS Research Map | TGRS