Photo-Induced Aliphatic C–H Amination Mediated by Hydrogen Atom Transfer of an Alkoxycarbonyloxyl Radical and Its Utilization for Diastereoselective Modification of Proline Residues in Peptides
)-H sites. By employing proline-containing C-H substrates, the protocol is amenable to precise manipulation of peptide skeletons through a diastereoselective process.
Authors
- Dandan Yuan
- Lihong Hu (ORCID: https://orcid.org/0000-0003-3792-2917)
- Hongdie Zhang
- Yangpeng Shen
- Jianming Yan (ORCID: https://orcid.org/0000-0001-6376-134X)
- Jiali Cao
- Yiqing Huang
- Anqi Ding
- Can Lu
- Yujian Mao
- Bohan Li
- Fei Xue
- Longyuan Zheng
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing Forestry University (CN)
Publication Details
- Journal
- Journal of the American Chemical Society
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1021/jacs.6c03204
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chongqing Medical University
- Natural Science Foundation of Jiangsu Province
- Jiangsu Provincial Department of Education
- Nanjing University of Chinese Medicine