Spectroscopic Quantification of Plasma Free Hemoglobin Based on Paired Domain Adaptation and Orthogonality Constraints
OBJECTIVE: We propose a paired domain-adaptation deep regression method for multi-pathlength spectroscopy to quantify plasma free hemoglobin (FHB) robustly across measurement conditions. METHODS: on the raw scale. RESULTS: = 0.748 ± 0.088. CONCLUSION: The method improves cross-domain robustness and interpretability for plasma FHB prediction.
Authors
- Haiyue Lv
- Mengqiu Zhang (ORCID: https://orcid.org/0000-0003-1662-4785)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Biophotonics
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1002/jbio.70266
- Primary Topic
- Spectroscopy and Chemometric Analyses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shandong Province