Wildland-Urban Interface Fires: Toxic Physicochemical Properties of Emitted Particulate Matter and Impacts on Lung Macrophages
) 20 times higher than biomass fire PM. Additionally, exposure of THP-1 macrophages to WUI fire PM, but not biomass fire PM, caused significant reductions in viability and mitochondrial potential, significantly decreased phagocytosis of 1 μm beads, and substantial dysregulation of gene expression. These findings suggest that WUI fire PM exposure may be more hazardous than wildland fire PM exposure, likely due to differences in their chemical profiles.
Authors
- Irini Tsiodra (ORCID: https://orcid.org/0000-0001-5392-8986)
- Luke Fritzky (ORCID: https://orcid.org/0009-0003-3061-2673)
- Shuo Xiao (ORCID: https://orcid.org/0000-0001-7225-9132)
- L. Calderon (ORCID: https://orcid.org/0000-0002-8163-3736)
- Georgios A. Kelesidis (ORCID: https://orcid.org/0000-0003-4220-9649)
- Glen M. DeLoid (ORCID: https://orcid.org/0000-0002-6855-9172)
- Nachiket Vaze
- Philip Demokritou (ORCID: https://orcid.org/0000-0002-2484-9143)
- Lila Bazina (ORCID: https://orcid.org/0009-0001-3266-3824)
- Jose Guillermo Cedeño Laurent
- Audrey Gaskins
- Nikolas Mihalopoulos
Institutions
- University of Crete (GR)
- Emory University (US)
- Faculty (United Kingdom) (GB)
- Rutgers Sexual and Reproductive Health and Rights (NL)
- Environmental and Occupational Health Sciences Institute (US)
- National Observatory of Athens (GR)
- NOAA Chemical Sciences Laboratory (US)
- Institute for Sustainable Development (ET)
- Institute for Environmental Research
- Delft University of Technology (NL)
Publication Details
- Journal
- Environmental Science & Technology
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1021/acs.est.5c16340
- Citations
- 1
- Primary Topic
- Fire effects on ecosystems
- Type
- article
- Field-Weighted Citation Impact
- 18.40
Funders
- National Science Foundation
- National Institute of Environmental Health Sciences