Preparation of PSA-DOX/ICG-Lip and Evaluation of Its Efficacy Against Cervical Cancer

: The microfluidically prepared PSA-DOX/ICG-Lip possesses high drug encapsulation efficiency, uniform particle size, good stability and sustained drug release properties. It can efficiently convert light energy into thermal energy, target neutrophils to enhance the affinity for cervical cancer cells, and exert a synergistic anti-tumor effect via the combination of chemotherapy and photothermal therapy, which provides a promising nanoplatform for the precise treatment of cervical cancer.

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Publication Details

Journal
Pharmaceutics
Published
2026-03-31
DOI
https://doi.org/10.3390/pharmaceutics18040434
Primary Topic
Advanced Drug Delivery Systems
Type
article
Field-Weighted Citation Impact
0.00

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article

Preparation of PSA-DOX/ICG-Lip and Evaluation of Its Efficacy Against Cervical Cancer

Jingya Bai, Qi Shen, Guorui Zhu, Jun Huang et al.
Pharmaceutics
Advanced Drug Delivery Systems
article

Preparation of PSA-DOX/ICG-Lip and Evaluation of Its Efficacy Against Cervical Cancer

Jingya Bai, Qi Shen, Guorui Zhu, Jun Huang, Wenjun Su, Qian Zhang, Xiaohui Tang, Mukadaisi Amuti, Mei Wang, Jian Yang
article en

Abstract

: The microfluidically prepared PSA-DOX/ICG-Lip possesses high drug encapsulation efficiency, uniform particle size, good stability and sustained drug release properties. It can efficiently convert light energy into thermal energy, target neutrophils to enhance the affinity for cervical cancer cells, and exert a synergistic anti-tumor effect via the combination of chemotherapy and photothermal therapy, which provides a promising nanoplatform for the precise treatment of cervical cancer.

PharmaceuticsVol. 18(4)
Xinjiang Medical University (CN)
Xinjiang Uygur Autonomous Region Department of Education
Openalex Percentile: Top 38%
Advanced Drug Delivery Systems
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