Genetic Variation in CYP2B6, UGT1A4 and Sulfotransferases Is Associated with Disease-Free Survival in South African Breast Cancer Patients Treated with Tamoxifen
: These exploratory findings highlight the need for more inclusive pharmacogenomic research and point to potential biomarkers for optimizing tamoxifen therapy in African populations.
Authors
- Aron Abera
- Bianca Kruger (ORCID: https://orcid.org/0000-0003-1027-6660)
- Collet Dandara (ORCID: https://orcid.org/0000-0002-5925-4895)
- Emile R. Chimusa (ORCID: https://orcid.org/0000-0001-8846-2047)
- Delva Shamley (ORCID: https://orcid.org/0000-0003-2355-6629)
- Jesmika Singh
Institutions
- South African Medical Research Council (ZA)
- University of Cape Town (ZA)
- Northumbria University (GB)
- Inqaba Biotechnical Industries
Publication Details
- Journal
- Journal of Personalized Medicine
- Published
- 2026-03-31
- DOI
- https://doi.org/10.3390/jpm16040188
- Primary Topic
- Pharmacogenetics and Drug Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- South African Medical Research Council
- University of Cape Town
- Medical Research Council