An Analysis of Studies Testing Digital Interventions to Inoculate Against Misinformation: A Systematic Review

The proliferation of misinformation has stimulated research into games and videos to reduce susceptibility to misinformation via psychological inoculation. This research field applies several recent extensions of inoculation theory in novel ways, posing the question of whether such interventions are indeed producing inoculation effects. We conducted a systematic review ( k = 72) to establish the strength of the links between inoculation theory and the outcomes of the tests. We found that the studies did not pose hypotheses relating to the core factors of inoculation theory: threat conferral and counterarguing. Moreover, empirical designs and analyses have introduced confounding factors. Therefore, links between psychological inoculation theory and the tests are weak, and the question of whether the interventions inoculate remains unbroached. We recommend that future research include theoretically relevant variables in improved empirical tests and that researchers exercise caution in interpreting the results of existing studies as representative of psychological inoculation effects.

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Publication Details

Journal
Communication Research
Published
2026-03-31
DOI
https://doi.org/10.1177/00936502251411467
Primary Topic
Misinformation and Its Impacts
Type
article
Field-Weighted Citation Impact
0.00

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article

An Analysis of Studies Testing Digital Interventions to Inoculate Against Misinformation: A Systematic Review

Marieke L. Fransen, Mariska Kleemans, Aart van Stekelenburg, Daniel Loughnan et al.
Communication Research
Misinformation and Its Impacts
article

An Analysis of Studies Testing Digital Interventions to Inoculate Against Misinformation: A Systematic Review

Marieke L. Fransen, Mariska Kleemans, Aart van Stekelenburg, Daniel Loughnan, J. Loes Pouwels
article en

Abstract

The proliferation of misinformation has stimulated research into games and videos to reduce susceptibility to misinformation via psychological inoculation. This research field applies several recent extensions of inoculation theory in novel ways, posing the question of whether such interventions are indeed producing inoculation effects. We conducted a systematic review ( k = 72) to establish the strength of the links between inoculation theory and the outcomes of the tests. We found that the studies did not pose hypotheses relating to the core factors of inoculation theory: threat conferral and counterarguing. Moreover, empirical designs and analyses have introduced confounding factors. Therefore, links between psychological inoculation theory and the tests are weak, and the question of whether the interventions inoculate remains unbroached. We recommend that future research include theoretically relevant variables in improved empirical tests and that researchers exercise caution in interpreting the results of existing studies as representative of psychological inoculation effects.

Communication Research
Radboud University Nijmegen (NL)
Radboud Universiteit
Openalex Percentile: Top 31%
Misinformation and Its Impacts
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An Analysis of Studies Testing Digital Interventions to Inoculate Against Misinformation: A Systematic Review — Marieke L. Fransen, Mariska Kleemans, et al. · Communication Research (2026) | TGRS Research Map | TGRS