Effect of a Synbiotic Combination of 2′-Fucosyllactose and Lactiplantibacillus plantarum Hi188 on Skeletal Growth and Gut Microbial Metabolism in Growing Mice

Medium doses of synbiotic supplementation were associated with improved skeletal growth and bone quality during development, alongside coordinated modulation of bone remodeling and gut microbial metabolic activity. These findings suggest its potential as a functional nutritional strategy for supporting early bone health.

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Publication Details

Journal
Nutrients
Published
2026-03-31
DOI
https://doi.org/10.3390/nu18071123
Primary Topic
Infant Nutrition and Health
Type
article
Field-Weighted Citation Impact
0.00

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article

Effect of a Synbiotic Combination of 2′-Fucosyllactose and Lactiplantibacillus plantarum Hi188 on Skeletal Growth and Gut Microbial Metabolism in Growing Mice

Xiangyu Bian, Jin Li, Linjun Wu, Fangshu Shi et al.
Nutrients
Infant Nutrition and Health
article

Effect of a Synbiotic Combination of 2′-Fucosyllactose and Lactiplantibacillus plantarum Hi188 on Skeletal Growth and Gut Microbial Metabolism in Growing Mice

Xiangyu Bian, Jin Li, Linjun Wu, Fangshu Shi, Xiaoqiong Li, Yang Li, Xin Wang
article en

Abstract

Medium doses of synbiotic supplementation were associated with improved skeletal growth and bone quality during development, alongside coordinated modulation of bone remodeling and gut microbial metabolic activity. These findings suggest its potential as a functional nutritional strategy for supporting early bone health.

NutrientsVol. 18(7)
China North Industries Group Corporation (China) (CN), ZheJiang Academy of Agricultural Sciences (CN), Ministry of Agriculture and Rural Affairs (CN)
Zhejiang Academy of Agricultural Sciences
Zero hunger
Openalex Percentile: Top 40%
Infant Nutrition and Health
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