A Complex Case of Renal Artery Stenosis in a 3-Year-Old Patient with Neurofibromatosis Type 1 and Secondary Hypertension

We describe a case of a 3-year-old girl with neurofibromatosis type 1 presenting with arterial hypertension, in whom multimodal vascular imaging identified significant right renal artery stenosis. The patient was successfully treated with percutaneous transluminal renal angioplasty; however, post-procedural Doppler ultrasound revealed a transient vascular fistula. Changes in renal arterial inflow during the procedure may have temporarily altered pressure gradients, facilitating the opening of communication involving pre-existing compensatory collateral vessels. This case illustrates the diagnostic value of multimodal vascular imaging in pediatric hypertension and highlights a rare, self-limiting post-interventional vascular phenomenon.

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Publication Details

Journal
Diagnostics
Published
2026-03-31
DOI
https://doi.org/10.3390/diagnostics16071047
Primary Topic
Renal and Vascular Pathologies
Type
article
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article

A Complex Case of Renal Artery Stenosis in a 3-Year-Old Patient with Neurofibromatosis Type 1 and Secondary Hypertension

Bożena Werner, Rafał Maciąg, Mariusz Furmanek, Piotr Skrzypczyk et al.
Diagnostics
Renal and Vascular Pathologies
article

A Complex Case of Renal Artery Stenosis in a 3-Year-Old Patient with Neurofibromatosis Type 1 and Secondary Hypertension

Bożena Werner, Rafał Maciąg, Mariusz Furmanek, Piotr Skrzypczyk, Jakub Pytlos, Piotr Majcher
article en

Abstract

We describe a case of a 3-year-old girl with neurofibromatosis type 1 presenting with arterial hypertension, in whom multimodal vascular imaging identified significant right renal artery stenosis. The patient was successfully treated with percutaneous transluminal renal angioplasty; however, post-procedural Doppler ultrasound revealed a transient vascular fistula. Changes in renal arterial inflow during the procedure may have temporarily altered pressure gradients, facilitating the opening of communication involving pre-existing compensatory collateral vessels. This case illustrates the diagnostic value of multimodal vascular imaging in pediatric hypertension and highlights a rare, self-limiting post-interventional vascular phenomenon.

DiagnosticsVol. 16(7)
Medical University of Warsaw (PL)
Good health and well-being
Openalex Percentile: Top 35%
Renal and Vascular Pathologies
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