Cell type-specific control of cardiometabolic disease by the dileucine motif of the LDL receptor-related protein LRP1
mice differs from phenotypes observed in mice with LRP1 inactivation or NPxY motif mutation, thus highlighting a unique role of this LRP1 motif in mediating LRP1 functions.
Authors
- Karthickeyan Chella Krishnan (ORCID: https://orcid.org/0000-0002-4895-2495)
- April Haller (ORCID: https://orcid.org/0000-0002-0560-3033)
- David Y. Hui (ORCID: https://orcid.org/0000-0001-7333-2151)
- Emily Igel (ORCID: https://orcid.org/0000-0003-4036-2121)
- Melissa Asman
- Anja Jaeschke (ORCID: https://orcid.org/0000-0002-1347-733X)
- Ushodaya Mattam (ORCID: https://orcid.org/0000-0002-6448-5970)
- Jeyashree Alagarsamy
Institutions
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Journal of Biological Chemistry
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1016/j.jbc.2026.111421
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute