A Cascade Enzyme System Based on the Catalase-like Activity of Co-MQDs for Enhanced Visualized Tumor Combination Therapy

is then continuously split by CM, creating a positive-feedback loop that markedly amplifies the synergistic photothermal/catalytic therapeutic effect. Z-CM/GOx-HSA exhibited remarkable tumor-killing efficacy with a tumor inhibition rate of 93.7%, far superior to single-treatment strategies. Moreover, its nonautofluorescent visualization capability allows for real-time monitoring of the therapeutic process. Overall, this visualized enzyme cascade system effectively enhances tumor therapeutic efficacy and demonstrates excellent biosafety, providing strong support for the visualized tumor catalytic combination therapy.