Accuracy of noninvasive transcutaneous carbon dioxide monitoring in preterm neonates and very low birth weight infants compared with larger neonates

Purpose: in preterm neonates and VLBW infants (birth weight <1,500 g), and secondarily to explore how accuracy varies across different gestational age and birth weight strata. Methods: were measured simultaneously. Statistical analysis included linear regression, calculation of intraclass correlation coefficients (ICC), repeated measures correlation (rmcorr), and the repeated-measures Bland-Altman analysis. Results: < 0.001) was found in preterm neonates, particularly those with gestational age below 32 weeks, or a birth weight below 1,500 g. Similar correlations were observed in larger infants. Conclusions: is useful for continuous trend monitoring and may reduce the need for arterial sampling; however, confirmatory blood gas testing is recommended for extreme values or unstable clinical conditions.