Fluid balance, kidney function, and acute kidney injury risk in healthy men and women during simulated work-related heat stress
Although men are often thought to be at greater risk of dehydration during work-related heat stress due to lower fluid intake, the impact of biological sex on fluid balance remains unclear. This study shows that when cool fluids are available, men and women maintain similar fluid balance regardless of menstrual cycle phase, suggesting that sex does not influence dehydration risk during simulated work-related heat stress.
Authors
- Riley Ables
- Roger S. Zoh (ORCID: https://orcid.org/0000-0002-8066-1153)
- Curtis S. Goss (ORCID: https://orcid.org/0000-0002-9553-6603)
- Georgie Bruinvels (ORCID: https://orcid.org/0000-0002-9352-7228)
- Jessica A. Freemas (ORCID: https://orcid.org/0000-0001-7044-9549)
- Stephen J. Carter (ORCID: https://orcid.org/0000-0001-5625-0883)
- Robert F. Chapman (ORCID: https://orcid.org/0000-0001-7173-1976)
- Bruce Martin
- Tyler B. Baker
- Omkar Khandpekar
- Zachary J. Schlader
- Toby Mündel
Institutions
- Brock University (CA)
- Indiana University Bloomington (US)
- Indiana University Melvin and Bren Simon Comprehensive Cancer Center
- Indiana University (US)
Publication Details
- Journal
- Journal of Applied Physiology
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1152/japplphysiol.00822.2025
- Primary Topic
- Thermoregulation and physiological responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American College of Sports Medicine
- Centers for Disease Control and Prevention