Fluorine-18 fluorodeoxyglucose PET/computed tomography–based scoring systems in oncology: pictorial review from clinical practice

[18F]FDG PET/CT (fluorine-18 fluorodeoxyglucose PET/computed tomography) imaging, integrating functional and anatomical information for various oncological workups, has shown better diagnostic accuracy than anatomical imaging alone, along with a prognostic role. But as a glucose analogue, it has multiple physiological/benign uptake in various organs and conditions in the human body, creating heterogeneity in reporting scan findings worldwide and thus making interpretation difficult for clinicians. Therefore, there is a growing demand to standardise PET/CT reports using validated scoring systems for better interpretation across various oncological evaluations. This article aimed to concisely compile and review various oncological [18F]FDG PET/CT scoring systems, as proposed in the literature and validated for routine practice in oncology, with appropriate representative images as examples for better understanding or interpretation.

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Publication Details

Journal
Nuclear Medicine Communications
Published
2026-03-31
DOI
https://doi.org/10.1097/mnm.0000000000002142
Primary Topic
Medical Imaging Techniques and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Fluorine-18 fluorodeoxyglucose PET/computed tomography–based scoring systems in oncology: pictorial review from clinical practice

Komal Bishnoi, Girish Kumar Parida, Kanhaiyalal Agrawal, Sai Sradha Patro et al.
Nuclear Medicine Communications
Medical Imaging Techniques and Applications
article

Fluorine-18 fluorodeoxyglucose PET/computed tomography–based scoring systems in oncology: pictorial review from clinical practice

Komal Bishnoi, Girish Kumar Parida, Kanhaiyalal Agrawal, Sai Sradha Patro, Kishan Subudhi, Gopinath Gnanasegaran
article en

Abstract

[18F]FDG PET/CT (fluorine-18 fluorodeoxyglucose PET/computed tomography) imaging, integrating functional and anatomical information for various oncological workups, has shown better diagnostic accuracy than anatomical imaging alone, along with a prognostic role. But as a glucose analogue, it has multiple physiological/benign uptake in various organs and conditions in the human body, creating heterogeneity in reporting scan findings worldwide and thus making interpretation difficult for clinicians. Therefore, there is a growing demand to standardise PET/CT reports using validated scoring systems for better interpretation across various oncological evaluations. This article aimed to concisely compile and review various oncological [18F]FDG PET/CT scoring systems, as proposed in the literature and validated for routine practice in oncology, with appropriate representative images as examples for better understanding or interpretation.

Nuclear Medicine Communications
Royal Free London NHS Foundation Trust (GB), The Royal Free Hospital (GB), All India Institute of Medical Sciences Bhubaneswar (IN), University College London (GB)
Openalex Percentile: Top 41%
Medical Imaging Techniques and Applications
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