Human milk bacteria assembled into functionally distinct synthetic communities in infant formula differently affect intestinal physiology and microbiota in neonatal mini-piglets
intestinal quadricellular model. Daily supplementation with these two SynComs modulated the composition of the gut microbiota and the gut physiology differently, particularly the intestinal immune signatures. In conclusion, the functional profile of bacteria within the HM microbiota may induce distinct developmental profiles of gut physiology in infants.
Authors
- Yves Le Loir (ORCID: https://orcid.org/0000-0002-0355-1065)
- Amandine Bellanger
- Sergine Even (ORCID: https://orcid.org/0000-0002-6836-2855)
- R. Janvier
- Patrice Dahirel
- Charles Le Bras
- Armelle Cahu
- Véronique Rome
- Gwénaëlle Randuineau
- Le Huërou-Luron, Isabelle, Luron
- L. Rault
- Marie-Bernadette Maillard
- Sophie Blat
- Sylvie Guérin
Institutions
- Inserm (FR)
- Institut Agro Rennes-Angers (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- CIC Rennes (FR)
- Science et Technologie du Lait et de l'Oeuf (FR)
- Nutrition, métabolismes et cancer (FR)
- Université de Rennes (FR)
Publication Details
- Journal
- mSystems
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1128/msystems.00106-26
- Primary Topic
- Infant Nutrition and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Conseil Régional de Bretagne
- Conseil Régional des Pays de la Loire