Deep learning image reconstruction optimizes coronary artery calcium quantification

Objective: To investigate the effects of deep learning reconstruction (DLR) on the image quality and quantification of coronary artery calcium (CAC). Materials and methods: Patients who underwent calcium scoring and coronary CT angiography examinations were retrospectively collected. The images of calcium scoring were reconstructed using filtered back projection (FBP), hybrid iterative reconstruction (HIR) and DLR algorithms. The CT value, image noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of aortic root and left ventricle were compared in three algorithms. Two radiologists scored the subjective image quality using a four-point scale. The quantification of CAC (Agatson score, calcium volume and mass) in FBP, HIR and DLR were calculated by automatic software. The risk classification of CAC were evaluated according to the Agatston score. Results: > 0.05). In risk classification analysis, DLR reduced the number of reclassification compared with HIR. Conclusion: DLR enhances the image quality and consistency of CAC quantification compared with FBP and HIR. Besides, DLR reduced risk reclassification relative to HIR.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-03-31
DOI
https://doi.org/10.3389/fcvm.2026.1639920
Primary Topic
Cardiac Imaging and Diagnostics
Type
article
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article

Deep learning image reconstruction optimizes coronary artery calcium quantification

Ting Wu, Y. Li, Xinru Ba, Ming Liu et al.
Frontiers in Cardiovascular Medicine
Cardiac Imaging and Diagnostics
article

Deep learning image reconstruction optimizes coronary artery calcium quantification

Ting Wu, Y. Li, Xinru Ba, Ming Liu, Jianjun Dong, Zhuangfei Ma, Min Zhang, Tao Zhou
article en

Abstract

Objective: To investigate the effects of deep learning reconstruction (DLR) on the image quality and quantification of coronary artery calcium (CAC). Materials and methods: Patients who underwent calcium scoring and coronary CT angiography examinations were retrospectively collected. The images of calcium scoring were reconstructed using filtered back projection (FBP), hybrid iterative reconstruction (HIR) and DLR algorithms. The CT value, image noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of aortic root and left ventricle were compared in three algorithms. Two radiologists scored the subjective image quality using a four-point scale. The quantification of CAC (Agatson score, calcium volume and mass) in FBP, HIR and DLR were calculated by automatic software. The risk classification of CAC were evaluated according to the Agatston score. Results: > 0.05). In risk classification analysis, DLR reduced the number of reclassification compared with HIR. Conclusion: DLR enhances the image quality and consistency of CAC quantification compared with FBP and HIR. Besides, DLR reduced risk reclassification relative to HIR.

Frontiers in Cardiovascular MedicineVol. 13
Yuhuangding Hospital (CN), Yantaishan Hospital (CN), Jinan City People's Hospital (CN), Shandong First Medical University (CN)
Openalex Percentile: Top 42%
Cardiac Imaging and Diagnostics
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Deep learning image reconstruction optimizes coronary artery calcium quantification — Ting Wu, Y. Li, et al. · Frontiers in Cardiovascular Medicine (2026) | TGRS Research Map | TGRS