Digital, remotely delivered management interventions for adult asthma: a systematic review and meta-analysis

Background: Remote, digitally delivered asthma management is increasingly used in routine care, but its long-term impact on core clinical outcomes in adults remains uncertain. Methods: % predicted at 12 months. Random-effects models generated pooled mean differences (MD) or risk ratios. Results: % predicted, moderate for 12-month mini-AQLQ, and very low for ACQ and 6-month mini-AQLQ due to risk of bias and inconsistency. Conclusions: Interactive remote digital management statistically significant but modest improvements in quality of life and symptom control, which did not reach the established MCID of 0.5. These findings support structured, clinician-supported digital interventions as a useful, though limited, adjunct to standard pharmacologic management for adult asthma. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251133851, identifier: CRD420251133851.