Tailoring the Charge and pH Responsiveness of Nanoparticles by Combining LCST Smart Polymers and Polyelectrolytes on Surfaces

), and zeta potential (ζ-Pot). The isoelectric point of each system was determined, as was the relative buffering capacity of the LCST-NP, which indicated only a few LCST polymers per NP, which limited stability and charge. To overcome this, PE layers were deposited in a layer-by-layer (LbL) manner, forming PE/LCST-NP conjugates, which had layer-dependent charge and improved stability, while retaining the LCST properties of the base layer.