Lipidomic dataset of optic nerves from the silicone oil–induced ocular hypertension mouse model
= 6 per time point (3 males, 3 females). Lipids were extracted by a modified Bligh Dyer protocol and profiled by untargeted LC-MS/MS on a Vanquish Horizon ultrahigh performance liquid chromatography (UHPLC) coupled to a Thermo Q Exactive Orbitrap. Raw files were processed in LipidSearch 5.1, and statistical analysis was conducted through MetaboAnalyst 6.0. This data is available through Metabolomics Workbench, Study ID: ST004446.
Authors
- David C. Holden
- Zixuan Hao
- Isabella Moceri
- Sanjoy K. Bhattacharya (ORCID: https://orcid.org/0000-0003-3759-647X)
- Rui Ma
- Yu Hong
- Yuan Liu
- Wenxuan Li
- Richard B. Lee
Institutions
- University of Miami (US)
Publication Details
- Journal
- Data in Brief
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1016/j.dib.2026.112739
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Glaucoma Research Foundation
- Research to Prevent Blindness
- Walter G. Ross Foundation
- National Institutes of Health
- National Eye Institute
- Common Fund