Association between adenomyosis and maternal and neonatal outcomes: a systematic review and meta-analysis

Background: Adenomyosis has garnered increasing attention for its association with adverse pregnancy outcomes in recent years. However, findings across studies remain inconsistent. This meta-analysis of cohort studies evaluated the impact of adenomyosis on maternal and perinatal outcomes. Methods: statistics, and 95% prediction intervals (PIs). Results: < 0.05). Subgroup analyses indicated that women undergoing assisted reproductive technology continued to experience diminished clinical pregnancy and live birth rates, as well as increased risks of miscarriage, placenta previa, LBW, and pre-eclampsia. Moreover, the findings suggested that Asian populations may be more susceptible to pregnancy complications and adverse obstetric outcomes compared to Caucasian populations. Conclusion: Adenomyosis is associated with various adverse pregnancy and neonatal outcomes. Pregnancies affected by this condition should be classified as high-risk, necessitating careful medical supervision and prompt, tailored interventions to mitigate potential complications throughout gestation.