Molecularly Imprinted Aggregation-Induced Electrochemiluminescence Interface Based on Quinoline-Malononitrile Nanomaterials for Specific and Ultrasensitive Recognition of Zearalenone
, providing a bright and stable transduction platform. An electropolymerized imprinting layer was then constructed in the presence of ZEN and subsequently eluted to generate specific binding cavities, leading to a characteristic "decrease-recovery-decrease" ECL evolution during film growth, template removal, and target rebinding. Under optimized conditions, ZEN induced pronounced ECL quenching with a good linear response from 0.01 to 100 ng/mL and a detection limit of 7.24 pg/mL. The sensor also showed excellent reproducibility and operational stability, and achieved satisfactory recoveries in corn flour, wheat flour, and beer samples. Collectively, this work demonstrates an effective strategy to integrate bright AIECL organic emitters with robust MIP recognition for selective and sensitive ZEN monitoring in complex food matrices.
Authors
- Peiyao Du
- Shaoyu Zou
- Meluze Luobu
- Xiaoquan Lu
- Hui Xiao
- Zhengang Han
- Shuying Li
Institutions
- Northwest Normal University (CN)
- Northwest A&F University (CN)
Publication Details
- Journal
- Analytical Chemistry
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1021/acs.analchem.6c01356
- Primary Topic
- Advanced biosensing and bioanalysis techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China