Surface versus Nanocatalyst-Induced Matrix Bubbles Govern Temperature-Dependent Biofilm Removal
decomposition coupled with enhanced bubble expansion and rupture, which deliver strong mechanical perturbation within the biofilm matrix. Importantly, nanocatalyst-induced matrix bubbles effectively removed biofilm from complex surgical instrument geometries and acted synergistically with autoclaving. This study therefore establishes temperature-controlled, nanocatalyst-mediated matrix bubble dynamics as a physical strategy for overcoming biofilm resistance in clinical and industrial settings.
Authors
- Guillermo L. Monroy (ORCID: https://orcid.org/0000-0002-3669-8514)
- Simon A. Rogers (ORCID: https://orcid.org/0000-0002-3432-5044)
- Junggeon Park
- Stephen A. Boppart (ORCID: https://orcid.org/0000-0002-9386-5630)
- Joo Hun Lee (ORCID: https://orcid.org/0009-0008-0084-2407)
- Eun‐Jin Park (ORCID: https://orcid.org/0000-0002-0103-5702)
- Jiye Lee (ORCID: https://orcid.org/0000-0001-6723-4010)
- Hyunjoon Kong
- Yujin Ahn
- Adam A. Markowicz
- Christian Hurd
Institutions
- University of Illinois Urbana-Champaign (US)
- Illinois College (US)
- National Institute of Biomedical Imaging and Bioengineering (US)
- Chan Zuckerberg Initiative (United States) (US)
- Seoul National University Dental Hospital (KR)
- Chan Zuckerberg Biohub Chicago
Publication Details
- Journal
- ACS Applied Materials & Interfaces
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1021/acsami.6c00615
- Primary Topic
- Innovative Microfluidic and Catalytic Techniques Innovation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- Ministry of Trade, Industry and Energy
- National Institutes of Health
- National Institute of Biomedical Imaging and Bioengineering