Bedside lung ultrasound versus chest CT in critically ill patients: a cross-sectional diagnostic accuracy study

Study aim: Evluate bedside lung ultrasound (LUS) diagnostic accuracy versus chest computed tomography (CT) in adult ICU patients with respiratory distress. Design and methods: Single-center, cross-sectional study of 200 paired LUS-CT examinations. LUS was performed within 12 h, scanning six zones per hemithorax and classifying findings into A-lines, C1 (pneumonia), C2 (atelectasis), B1, B2 (interstitial patterns), pleural effusion, and emphysema. Diagnostic performance metrics included sensitivity, specificity, predictive values, likelihood ratios, and ROC analysis. Key results: CT showed consolidations (60.5%), pleural effusions (42.5%), interstitial syndrome (28.5%), ground-glass opacities (26%), and emphysema (23.5%). LUS detected C1 in 66.5% (posterior-inferior predominance), B2 in 40.5%, B1 in 40%, pleural effusions in 38.5%, C2 in 13.5%, and emphysema in 16.5%. Overall concordance with CT was 81%. LUS had very high specificity for pleural effusion (Sp = 96.5%, PLR = 24.5, accuracy = 91.9%) and atelectasis (Sp = 93.7%, NPV = 97.6%, PLR = 12.6, accuracy = 92.3%), very high sensitivity for alveolar-interstitial syndrome (Se = 96.2%, NPV = 98.3%, NLR = 0.05), and good sensitivity for consolidations (Se = 89.3%). Conclusion: LUS is a reliable bedside tool that can reduce CT use, radiation exposure, and enable dynamic monitoring; structured training is essential.

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Journal
Frontiers in Medicine
Published
2026-03-31
DOI
https://doi.org/10.3389/fmed.2026.1724227
Primary Topic
Ultrasound in Clinical Applications
Type
article
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article

Bedside lung ultrasound versus chest CT in critically ill patients: a cross-sectional diagnostic accuracy study

Lynda Messaoud, Ahlem Trifi, Eya Seghir, Rochdi Nasri et al.
Frontiers in Medicine
Ultrasound in Clinical Applications
article

Bedside lung ultrasound versus chest CT in critically ill patients: a cross-sectional diagnostic accuracy study

Lynda Messaoud, Ahlem Trifi, Eya Seghir, Rochdi Nasri, Asma Ouhibi, Asma Mehdi, Sami Abdellatif, Hounaida Galai
article en

Abstract

Study aim: Evluate bedside lung ultrasound (LUS) diagnostic accuracy versus chest computed tomography (CT) in adult ICU patients with respiratory distress. Design and methods: Single-center, cross-sectional study of 200 paired LUS-CT examinations. LUS was performed within 12 h, scanning six zones per hemithorax and classifying findings into A-lines, C1 (pneumonia), C2 (atelectasis), B1, B2 (interstitial patterns), pleural effusion, and emphysema. Diagnostic performance metrics included sensitivity, specificity, predictive values, likelihood ratios, and ROC analysis. Key results: CT showed consolidations (60.5%), pleural effusions (42.5%), interstitial syndrome (28.5%), ground-glass opacities (26%), and emphysema (23.5%). LUS detected C1 in 66.5% (posterior-inferior predominance), B2 in 40.5%, B1 in 40%, pleural effusions in 38.5%, C2 in 13.5%, and emphysema in 16.5%. Overall concordance with CT was 81%. LUS had very high specificity for pleural effusion (Sp = 96.5%, PLR = 24.5, accuracy = 91.9%) and atelectasis (Sp = 93.7%, NPV = 97.6%, PLR = 12.6, accuracy = 92.3%), very high sensitivity for alveolar-interstitial syndrome (Se = 96.2%, NPV = 98.3%, NLR = 0.05), and good sensitivity for consolidations (Se = 89.3%). Conclusion: LUS is a reliable bedside tool that can reduce CT use, radiation exposure, and enable dynamic monitoring; structured training is essential.

Frontiers in MedicineVol. 13
Hôpital La Rabta (TN), Tunis El Manar University (TN)
Good health and well-being
Openalex Percentile: Top 27%
Ultrasound in Clinical Applications
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