Molecular epidemiological analysis of Vibrio parahaemolyticus in foodborne diseases in Liaoning province, 2023–2024

Introduction: Vibrio parahaemolyticus (VP) is a major pathogen causing foodborne diseases, and Liaoning Province, a coastal region with high seafood consumption and production, faces a notable risk of VP-associated foodborne infections. Clarifying the molecular epidemiological characteristics of VP in this region is critical for targeted prevention and control of such diseases. This study aimed to investigate the molecular epidemiological features, virulence gene profiles, and antibiotic resistance gene distribution of VP isolated from foodborne disease cases in Liaoning Province during 2023-2024, providing precise data support for VP prevention and control. Methods: collected in Liaoning province from 2023 to 2024. Multilocus sequence typing (MLST), virulence gene identification, and antibiotic resistance gene detection were conducted and combined with epidemiological surveillance data to analyze the association between genetic and epidemiological characteristics. Results: B had the highest deletion rate (95.79%). MLST analysis identified 11 sequence type based on typing results, with ST3 as the dominant epidemic strain (94.25%). Conclusion: foodborne diseases.