Single-cell spatial atlas of the aging human breast
T cells, contrasted by younger tissues in which B cells were most enriched. Our multiscale atlas extensively details an unexpected general decline of breast tissue with age and reveals its changing spatial context.
Authors
- Shimrit Mayer (ORCID: https://orcid.org/0000-0003-4634-3562)
- Xiao Qian Wang (ORCID: https://orcid.org/0000-0001-5269-1219)
- Ellen Schrader (ORCID: https://orcid.org/0009-0000-8067-7377)
- Samuel Aparício (ORCID: https://orcid.org/0000-0002-0487-9599)
- Sean Beatty (ORCID: https://orcid.org/0000-0001-6819-7071)
- Cristina Flores
- Pulkit Gupta
- Andrew Roth
- Neus Masqué Soler
- Eric Lee
- H. Raza Ali
Institutions
- BC Cancer Agency (CA)
- University of British Columbia (CA)
- University of Cambridge (GB)
- Addenbrooke's Hospital (GB)
Publication Details
- Journal
- Nature Aging
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1038/s43587-026-01104-3
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00