Virulence, antimicrobial resistance, and mobile genetic elements profile of Clostridium perfringens isolated from animal derived food chains
from animal-derived food chains, showing that prophage gain/loss, IS expansion, and plasmid carriage vary semi-independently and jointly shape ARGs and virulence profiles. It highlights the need for lineage-resolved genomic surveillance that considers both conserved chromosomal scaffold and dynamic MGE landscape to control strategies for this zoonotic pathogen.
Authors
- Zhaoyu Chang
- Haoyu Zhao (ORCID: https://orcid.org/0009-0007-2523-1031)
- Deyang Guo
- Xinru Wang
- Juan Wang
- Kailiang Han
Institutions
- North West Agriculture and Forestry University (CN)
Publication Details
- Journal
- One Health
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1016/j.onehlt.2026.101398
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 0.00