Virulence, antimicrobial resistance, and mobile genetic elements profile of Clostridium perfringens isolated from animal derived food chains

from animal-derived food chains, showing that prophage gain/loss, IS expansion, and plasmid carriage vary semi-independently and jointly shape ARGs and virulence profiles. It highlights the need for lineage-resolved genomic surveillance that considers both conserved chromosomal scaffold and dynamic MGE landscape to control strategies for this zoonotic pathogen.

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Publication Details

Journal
One Health
Published
2026-03-31
DOI
https://doi.org/10.1016/j.onehlt.2026.101398
Primary Topic
Clostridium difficile and Clostridium perfringens research
Type
article
Field-Weighted Citation Impact
0.00
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article

Virulence, antimicrobial resistance, and mobile genetic elements profile of Clostridium perfringens isolated from animal derived food chains

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One Health
Clostridium difficile and Clostridium perfringens research
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Virulence, antimicrobial resistance, and mobile genetic elements profile of Clostridium perfringens isolated from animal derived food chains

Zhaoyu Chang, Haoyu Zhao, Deyang Guo, Xinru Wang, Juan Wang, Kailiang Han
article en

Abstract

from animal-derived food chains, showing that prophage gain/loss, IS expansion, and plasmid carriage vary semi-independently and jointly shape ARGs and virulence profiles. It highlights the need for lineage-resolved genomic surveillance that considers both conserved chromosomal scaffold and dynamic MGE landscape to control strategies for this zoonotic pathogen.

One HealthVol. 22
North West Agriculture and Forestry University (CN)
Zero hunger
Openalex Percentile: Top 26%
Clostridium difficile and Clostridium perfringens research
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