A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFECT OF PANCHTIKTA PANCHPRASRITIKA BASTI AND NISHAKATAKADI YOGA IN MANAGEMENT OF MADHUMEHA WITH SPECIAL REFERENCE TO DIABETES MELLITUS TYPE 2

Background: Madhumeha is described in Ayurveda under the broad category of Prameha and is characterized by excessive urination and metabolic disturbances. It closely resembles Type 2 Diabetes Mellitus in modern medicine. Due to sedentary lifestyle, improper dietary habits, and stress, the incidence of diabetes is increasing rapidly worldwide. Ayurveda offers several therapeutic modalities such as Shodhana and Shamana therapies for the management of this condition Aim: To compare the effect of Panchatikta Panchprasritika Basti along with oral Nishakatakadi Yoga and oral Nishakatakadi Yoga in the management of Madhumeha with special reference to diabetes mellitus type-2. Materials and methods: The present clinical study entitled ‘A Comparative Clinical study to evaluate the effect of Panchatikta Panchprasritika Basti and Nishakatakadi Yoga in Management of Madhumeha with special reference to Diabetes Mellitus Type 2’ was carried out on 40 patients divided into 2 groups. One group was given Panchatikta Panchprasritika Basti for 15 days and oral Nishakatakadi Yoga for 15 days and another group of patients will be given oral Nishakatakadi Yoga for 1 month. The “Wilcoxon matched pairs signed rank test” was used while for parametric data, “Paired t test” was used and results calculated in each group. For calculating the inter group comparison, “Mann Whitney and the Unpaired t-test” was used for non-parametric and parametric data respectively. Results: Significant improvement was observed in symptoms like Prabhuta Mutrata, Trishna, Kshudha Adhikya, and Nidra Adhikya in both groups. Objective parameters such as Fasting Blood Sugar and Post-Prandial Blood Sugar also showed statistically significant improvement. Conclusion: Both treatment modalities showed beneficial effects in the management of Madhumeha. However, Panchatikta Panchprasritika Basti combined with Nishakatakadi Yoga showed comparatively better results.