Integrating chronic inflammation and hypoxia

High-grade serous ovarian carcinoma (HGSOC) is marked by late diagnosis and chemoresistance, partly driven by chronic inflammation and hypoxia in the tumor microenvironment. Hypoxia-inducible factor 1-alpha (HIF-1a) is a key regulator of these processes

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Publication Details

Journal
DiRROS repository (University of Maribor)
Published
2026-03-26
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
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article

Integrating chronic inflammation and hypoxia

Borut Kobal, Katarina Černe, David Lukanović, Sara Polajžer et al.
DiRROS repository (University of Maribor)
Cancer, Hypoxia, and Metabolism
article

Integrating chronic inflammation and hypoxia

Borut Kobal, Katarina Černe, David Lukanović, Sara Polajžer, Erik Škof
article en

Abstract

High-grade serous ovarian carcinoma (HGSOC) is marked by late diagnosis and chemoresistance, partly driven by chronic inflammation and hypoxia in the tumor microenvironment. Hypoxia-inducible factor 1-alpha (HIF-1a) is a key regulator of these processes

DiRROS repository (University of Maribor)
University of Ljubljana (SI), Ljubljana University Medical Centre (SI), Institute of Oncology Ljubljana (SI)
Good health and well-being
Openalex Percentile: Top 3%
Cancer, Hypoxia, and Metabolism
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