YOLOECL a lightweight model for blood cell detection in intelligent medical testing equipment

Accurate and efficient blood cell detection in microscopic images remains challenging due to dense object distribution, frequent occlusion, and the small size of platelets, which often lead to missed detections and redundant computations in existing detectors. To address these issues, we propose YOLO-ECL, a lightweight blood cell detection framework built upon YOLOv11n. YOLO-ECL introduces three targeted improvements: (i) C3k2_EMBC, which replaces the original C3k2 backbone module by integrating MBConv with Squeeze-and-Excitation (SE) attention to enhance fine-grained feature extraction for minute cells; (ii) ContextGuidedBlock_Down in the neck to jointly model local cues and surrounding context, improving robustness in dense and overlapping regions; and (iii) a Lightweight Shared Convolutional Detection head (LSCD) with a scale layer to reduce parameter redundancy while preserving multi-scale representation. Extensive experiments on the BCCD dataset (1344 images; RBC/WBC/platelet) show that YOLO-ECL achieves 95.8% [email protected] with only 2.50 M parameters and 6.1 GFLOPs, outperforming representative lightweight and mainstream YOLO variants under comparable settings. Moreover, cross-domain evaluation on the LISC dataset demonstrates improved generalization, reaching 86.2% [email protected] results on embedded platforms (Jetson Nano, RK3588, Snapdragon 8 Gen 2) confirm real-time inference (≥ 25 FPS) with low energy consumption (< 0.25 J/image) and limited memory footprint (< 600 MB), supporting practical integration into portable intelligent medical testing equipment.

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Publication Details

Journal
Discover Artificial Intelligence
Published
2026-03-29
DOI
https://doi.org/10.1007/s44163-026-01176-5
Primary Topic
Digital Imaging for Blood Diseases
Type
article
Field-Weighted Citation Impact
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article

YOLOECL a lightweight model for blood cell detection in intelligent medical testing equipment

Enqiang Liang, Minghui Zheng, Haiying Sun, Shengtao Li et al.
Discover Artificial Intelligence
Digital Imaging for Blood Diseases
article

YOLOECL a lightweight model for blood cell detection in intelligent medical testing equipment

Enqiang Liang, Minghui Zheng, Haiying Sun, Shengtao Li, Can Zhong, Huimin Lv
article en

Abstract

Accurate and efficient blood cell detection in microscopic images remains challenging due to dense object distribution, frequent occlusion, and the small size of platelets, which often lead to missed detections and redundant computations in existing detectors. To address these issues, we propose YOLO-ECL, a lightweight blood cell detection framework built upon YOLOv11n. YOLO-ECL introduces three targeted improvements: (i) C3k2_EMBC, which replaces the original C3k2 backbone module by integrating MBConv with Squeeze-and-Excitation (SE) attention to enhance fine-grained feature extraction for minute cells; (ii) ContextGuidedBlock_Down in the neck to jointly model local cues and surrounding context, improving robustness in dense and overlapping regions; and (iii) a Lightweight Shared Convolutional Detection head (LSCD) with a scale layer to reduce parameter redundancy while preserving multi-scale representation. Extensive experiments on the BCCD dataset (1344 images; RBC/WBC/platelet) show that YOLO-ECL achieves 95.8% [email protected] with only 2.50 M parameters and 6.1 GFLOPs, outperforming representative lightweight and mainstream YOLO variants under comparable settings. Moreover, cross-domain evaluation on the LISC dataset demonstrates improved generalization, reaching 86.2% [email protected] results on embedded platforms (Jetson Nano, RK3588, Snapdragon 8 Gen 2) confirm real-time inference (≥ 25 FPS) with low energy consumption (< 0.25 J/image) and limited memory footprint (< 600 MB), supporting practical integration into portable intelligent medical testing equipment.

Discover Artificial Intelligence
Wenzhou Hospital of Traditional Chinese Medicine (CN), Suzhou Traditional Chinese Medicine Hospital (CN), Hangzhou Hospital of Traditional Chinese Medicine (CN), Dezhou University (CN)
Affordable and clean energy
Openalex Percentile: Top 2%
Digital Imaging for Blood Diseases
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YOLOECL a lightweight model for blood cell detection in intelligent medical testing equipment — Enqiang Liang, Minghui Zheng, et al. · Discover Artificial Intelligence (2026) | TGRS Research Map | TGRS