A case report of pulmonary granuloma misdiagnosed as a malignant tumor

The objective of this study was to investigate the clinical characteristics and underlying causes of misdiagnosis in pulmonary granulomas, analyze the diagnostic challenges and differential diagnostic process, and improve clinical understanding in order to reduce misdiagnosis and optimize treatment. A retrospective analysis was conducted on a clinical case of pulmonary granuloma in a patient presenting with cough, sputum production, and hemoptysis. Initial computed tomography imaging revealed a malignant lung tumor. However, trans-thoracoscopy indicated that the lesion was an inflammatory granuloma, and the final diagnosis confirmed this finding. This case emphasizes that symptoms such as cough, sputum production, and hemoptysis may be indicative of pulmonary granulomas and may be misdiagnosed as malignant lung tumors. Therefore, a systematic and comprehensive diagnostic approach is essential. The integration of medical history, physical examination, and auxiliary tests, particularly pathological evaluation supported by positron emission tomography/computed tomography, can significantly reduce the risk of misdiagnosis, promote timely intervention, and improve the patient’s prognosis.

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Publication Details

Journal
Journal of International Medical Research
Published
2026-03-01
DOI
https://doi.org/10.1177/03000605261431567
Primary Topic
Vascular Anomalies and Treatments
Type
article
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article

A case report of pulmonary granuloma misdiagnosed as a malignant tumor

Li Juan, Chen Weiping
Journal of International Medical Research
Vascular Anomalies and Treatments
article

A case report of pulmonary granuloma misdiagnosed as a malignant tumor

Li Juan, Chen Weiping
article en

Abstract

The objective of this study was to investigate the clinical characteristics and underlying causes of misdiagnosis in pulmonary granulomas, analyze the diagnostic challenges and differential diagnostic process, and improve clinical understanding in order to reduce misdiagnosis and optimize treatment. A retrospective analysis was conducted on a clinical case of pulmonary granuloma in a patient presenting with cough, sputum production, and hemoptysis. Initial computed tomography imaging revealed a malignant lung tumor. However, trans-thoracoscopy indicated that the lesion was an inflammatory granuloma, and the final diagnosis confirmed this finding. This case emphasizes that symptoms such as cough, sputum production, and hemoptysis may be indicative of pulmonary granulomas and may be misdiagnosed as malignant lung tumors. Therefore, a systematic and comprehensive diagnostic approach is essential. The integration of medical history, physical examination, and auxiliary tests, particularly pathological evaluation supported by positron emission tomography/computed tomography, can significantly reduce the risk of misdiagnosis, promote timely intervention, and improve the patient’s prognosis.

Journal of International Medical ResearchVol. 54(3)
Macau University of Science and Technology (MO), The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine (CN), Affiliated Hospital of Guizhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 3%
Vascular Anomalies and Treatments
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A case report of pulmonary granuloma misdiagnosed as a malignant tumor — Li Juan, Chen Weiping · Journal of International Medical Research (2026) | TGRS Research Map | TGRS