Exploring heart rate variability as a biomarker for frailty: A narrative review

HRV is a highly promising physiological biomarker in the context of frailty, but further research is needed to clarify several aspects of its role. Its potential integration with other biomarkers may help confirm its validity and could contribute to identifying biomarker clusters relevant to personalized approaches.

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Publication Details

Journal
European Journal of Clinical Investigation
Published
2026-03-27
DOI
https://doi.org/10.1111/eci.70194
Primary Topic
Heart Rate Variability and Autonomic Control
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring heart rate variability as a biomarker for frailty: A narrative review

Stefania Peruzzo, Fiammetta Monacelli, Riccardo Balzano, Alessio Nencioni et al.
European Journal of Clinical Investigation
Heart Rate Variability and Autonomic Control
article

Exploring heart rate variability as a biomarker for frailty: A narrative review

Stefania Peruzzo, Fiammetta Monacelli, Riccardo Balzano, Alessio Nencioni, Luca Tagliafico, Silvia Ottaviani
article en

Abstract

HRV is a highly promising physiological biomarker in the context of frailty, but further research is needed to clarify several aspects of its role. Its potential integration with other biomarkers may help confirm its validity and could contribute to identifying biomarker clusters relevant to personalized approaches.

European Journal of Clinical InvestigationVol. 56(4)
Ospedale Policlinico San Martino (IT), University of Genoa (IT)
Openalex Percentile: Top 3%
Heart Rate Variability and Autonomic Control
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