Effects of repeated nalfurafine and VZTK35 treatments on fentanyl/cocaine mixture self-administration in a rat drug-vs.-food choice procedure
While candidate medications are needed for fentanyl and cocaine co-use, these results do not support the further evaluation of these KOR agonists for this purpose. However, these methods provide an empirical preclinical framework for studying fentanyl and cocaine interactions on reinforcement endpoints.
Authors
- Matthew L. Banks (ORCID: https://orcid.org/0000-0003-4949-5246)
- Celsey M. St. Onge (ORCID: https://orcid.org/0000-0002-9845-7118)
- Nicholas Heslep
- E. Andrew Townsend
- Yan Zhang
Institutions
- Scripps Research Institute (US)
- National Institute on Drug Abuse (US)
- Virginia Commonwealth University (US)
- Institute of Alcohol Studies (GB)
Publication Details
- Journal
- Psychopharmacology
- Published
- 2026-03-28
- DOI
- https://doi.org/10.1007/s00213-026-07047-2
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00