Therapeutic effects of imidazoline 2 receptor activation on lower urinary tract dysfunction in a mouse model of spinal cord injury

I2R activation in the lumbosacral spinal cord and bladder may provide an effective therapeutic strategy for SCI-induced LUTD.

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Publication Details

Journal
American Journal of Physiology-Renal Physiology
Published
2026-03-28
DOI
https://doi.org/10.1152/ajprenal.00457.2025
Primary Topic
Neuroscience of respiration and sleep
Type
article
Field-Weighted Citation Impact
0.00
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article

Therapeutic effects of imidazoline 2 receptor activation on lower urinary tract dysfunction in a mouse model of spinal cord injury

Tadanobu Chuyo Kamijo, Jonathan M. Beckel, Kanako Matsuoka, Stephanie L. Daugherty et al.
American Journal of Physiology-Renal Physiology
Neuroscience of respiration and sleep
article

Therapeutic effects of imidazoline 2 receptor activation on lower urinary tract dysfunction in a mouse model of spinal cord injury

Tadanobu Chuyo Kamijo, Jonathan M. Beckel, Kanako Matsuoka, Stephanie L. Daugherty, Sergei V. Karnup, Kang Jun Cho, Kazutoshi Fujita, Nobutaka Shimizu, Hirotsugu Uemura, Shingo Kimura, Naoki Yoshimura, Koichi Sugimoto, Mamoru Hashimoto
article en

Abstract

I2R activation in the lumbosacral spinal cord and bladder may provide an effective therapeutic strategy for SCI-induced LUTD.

American Journal of Physiology-Renal Physiology
University of Pittsburgh (US), Kōchi University (JP), Catholic University of Korea (KR), Kindai University (JP)
Good health and well-being
Openalex Percentile: Top 4%
Neuroscience of respiration and sleep
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Therapeutic effects of imidazoline 2 receptor activation on lower urinary tract dysfunction in a mouse model of spinal cord injury — Tadanobu Chuyo Kamijo, Jonathan M. Beckel, et al. · American Journal of Physiology-Renal Physiology (2026) | TGRS Research Map | TGRS