Late-Onset Sjögren disease: A different clinical entity?
Elderly-onset SjD demonstrates a distinct phenotype characterized by higher ILD prevalence, increased RF positivity, greater inflammatory activity, and more frequent artropathy and anemia compared to younger-onset groups. These findings highlight the need for age-tailored diagnostic vigilance, proactive ILD screening, and cautious use of immunosuppressants in older patients. Prospective multicenter studies are warranted to refine management strategies in this subgroup.
Authors
- Melih Kızıltepe (ORCID: https://orcid.org/0000-0001-6100-2024)
- Celil Barlas Cengiz (ORCID: https://orcid.org/0009-0002-6902-6017)
- Hüseyin Kaplan (ORCID: https://orcid.org/0000-0002-3292-0907)
- hanife oğuz (ORCID: https://orcid.org/0000-0002-8194-2395)
- Burcu Eren Cengiz (ORCID: https://orcid.org/0000-0001-6963-7542)
- Abdurrahman Soner Şenel
- Emel Oğuz Kökoğlu
- Tuğba Kahraman Denizhan
Institutions
- Aksaray University (TR)
- Kayseri Eğitim ve Araştırma Hastanesi (TR)
- Erciyes University (TR)
Publication Details
- Journal
- PubMed
- Published
- 2026-03-27
- DOI
- https://doi.org/10.36141/svdld.2026.18390
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 0.00