Epidemiological shifts in coxsackievirus A-induced hand, foot, and mouth disease in China, 2008–2024
Post-vaccination, EV-A71 incidence declined markedly, while CV-A6, CV-A10, CV-A16, and CV-A4 gradually became predominant, exhibiting distinct geographic and seasonal distributions. These findings underscore the evolving HFMD epidemiology in China and highlight the need for multivalent vaccines and sustained surveillance to effectively control HFMD.
Authors
- Lu Liu (ORCID: https://orcid.org/0000-0002-9488-7372)
- Xinyu Zhao (ORCID: https://orcid.org/0000-0002-5128-4424)
- Lan Yu (ORCID: https://orcid.org/0000-0002-7087-0883)
- Dandan Li
- H Z Zhao
- Haijing Shi
- Yun Liao
- Jingjing Wang
- Huiwen Zheng
- Heng Li
- Jun Li
Institutions
- Academy of Medical Sciences (GB)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Institut de Recherche Vaccinale (FR)
Publication Details
- Journal
- Expert Review of Vaccines
- Published
- 2026-03-28
- DOI
- https://doi.org/10.1080/14760584.2026.2652927
- Primary Topic
- Viral Infections and Immunology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00