Plasma proteomics implicates NOX-driven redox imbalance in degenerative cervical myelopathy: findings from the Australian MYelopathy Natural History Registry [AO Spine RECODE-DCM research priority number 5]
Findings support the feasibility of a plasma 'liquid biopsy' to augment diagnosis and monitoring. The modest cohort size and potential confounding by age and adiposity, absolute quantification, multivariate adjustment, and external validation are warranted to establish specificity and clinical utility.
Authors
- Stone Sima (ORCID: https://orcid.org/0000-0002-1675-1496)
- Valerie C. Wasinger (ORCID: https://orcid.org/0000-0001-5338-0869)
- Nashwa Najib (ORCID: https://orcid.org/0000-0002-7523-3082)
- Muhammad A. Alsherbiny (ORCID: https://orcid.org/0000-0001-9337-2441)
- Ryan O'Hare Doig
- Ashish D. Diwan
Institutions
- Royal Adelaide Hospital (AU)
- Cairo University (EG)
- Sutherland Hospital (AU)
- Emory University Orthopaedics and Spine Hospital (US)
- The Centre for Health (New Zealand) (NZ)
- Bioanalytica (Switzerland) (CH)
- South Australian Health and Medical Research Institute (AU)
- The University of Adelaide (AU)
Publication Details
- Journal
- Redox Report
- Published
- 2026-03-28
- DOI
- https://doi.org/10.1080/13510002.2026.2649669
- Primary Topic
- Cervical and Thoracic Myelopathy
- Type
- article
- Field-Weighted Citation Impact
- 0.00